Ruta Petraitiene Selected Research

isavuconazole

2/2021	Antifungal efficacy of isavuconazole and liposomal amphotericin B in a rabbit model of Exserohilum rostratum meningoencephalitis: A preclinical paradigm for management of CNS phaeohyphomycosis.
9/2020	Modeling Invasive Aspergillosis: How Close Are Predicted Antifungal Targets?
1/2020	Combination Therapy with Ibrexafungerp (Formerly SCY-078), a First-in-Class Triterpenoid Inhibitor of (1→3)-β-d-Glucan Synthesis, and Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis.
12/2018	Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole.
11/2017	In vitro combination therapy with isavuconazole against Candida spp.
1/2017	Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis.
1/2016	Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis.
1/2016	Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints.
11/2014	In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds.

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Ruta Petraitiene Research Topics

Disease

22	Invasive Pulmonary Aspergillosis 01/2021 - 01/2002
15	Infections 10/2021 - 07/2003
14	Body Weight (Weight, Body) 10/2021 - 01/2002
12	Aspergillosis 09/2020 - 01/2002
8	Lung Injury 09/2020 - 01/2002
7	Candidiasis (Moniliasis) 11/2017 - 06/2002
7	Pulmonary Aspergillosis 09/2013 - 01/2002
6	Meningoencephalitis 02/2021 - 01/2008
5	Pulmonary Infarction 01/2016 - 01/2002
5	Mycoses (Diseases, Fungus) 12/2015 - 12/2003
4	Infarction (Infarctions) 09/2020 - 06/2009
3	Pneumonia (Pneumonitis) 01/2020 - 12/2010
3	Invasive Candidiasis 11/2017 - 01/2006
2	Bacteremia 10/2021 - 01/2020
2	Phaeohyphomycosis 02/2021 - 03/2020
2	Neutropenia 03/2020 - 08/2015
2	Mucormycosis 12/2018 - 01/2013
2	Invasive Fungal Infections 05/2017 - 01/2017
2	Chronic Granulomatous Disease 01/2011 - 02/2006
1	Chronic Disease (Chronic Diseases) 10/2021
1	Candidemia 01/2021
1	Endophthalmitis (Ophthalmia) 01/2021
1	Germinoma 01/2017
1	Arthritis (Polyarthritis) 01/2016
1	Fungal Lung Diseases 11/2014
1	Fungal Meningitis 03/2013
1	Burkholderia Infections 01/2011
1	Inflammation (Inflammations) 01/2011
1	Bacterial Infections (Bacterial Infection) 01/2011
1	Bacterial Pneumonia 01/2009
1	Zygomycosis (Phycomycosis) 11/2008
1	Neoplasms (Cancer) 09/2008
1	Cryptococcosis 05/2007
1	Histoplasmosis 05/2007

Drug/Important Bio-Agent (IBA)

15	Amphotericin B (Amphotericin)FDA LinkGeneric 09/2020 - 01/2002
13	galactomannanIBA 01/2021 - 01/2002
12	Biomarkers (Surrogate Marker)IBA 09/2020 - 02/2006
9	Micafungin (FK463)FDA Link 02/2021 - 06/2002
9	isavuconazoleIBA 02/2021 - 11/2014
8	TriazolesIBA 02/2021 - 06/2003
7	liposomal amphotericin B FDA Link 02/2021 - 06/2002
7	EchinocandinsIBA 11/2017 - 01/2002
6	EnzymesIBA 01/2011 - 10/2004
4	Deoxycholic Acid (Sodium Deoxycholate)IBA 09/2020 - 01/2002
3	posaconazole FDA Link 01/2021 - 03/2020
3	Anidulafungin FDA Link 09/2020 - 06/2009
3	Caspofungin (Cancidas)FDA Link 09/2020 - 01/2002
3	Voriconazole (Vfend)FDA LinkGeneric 09/2020 - 06/2009
3	Methylprednisolone FDA LinkGeneric 03/2020 - 03/2013
3	deoxycholate drug combination amphotericin BIBA 05/2015 - 10/2006
3	AntigensIBA 09/2008 - 01/2002
3	ER 30346 (ravuconazole)IBA 10/2006 - 06/2003
2	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 10/2021 - 10/2004
2	ProdrugsIBA 01/2021 - 01/2016
2	Pharmaceutical PreparationsIBA 09/2020 - 01/2002
2	Antifungal AgentsIBA 09/2020 - 01/2017
2	ibrexafungerpIBA 09/2020 - 01/2020
2	PolyenesIBA 11/2017 - 12/2003
2	Nucleic AcidsIBA 01/2017 - 11/2014
2	HaptoglobinsIBA 06/2014 - 12/2010
2	Proteins (Proteins, Gene)FDA Link 06/2014 - 12/2010
2	C-Reactive ProteinIBA 06/2014 - 12/2010
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2011 - 02/2006
2	polyglucosanIBA 11/2010 - 11/2008
2	Dihydrotachysterol (AT 10)IBA 06/2009 - 05/2005
2	Isoleucine-tRNA LigaseIBA 05/2005 - 10/2004
2	2- amino- 4- methylenecyclopentane- 1- carboxylic acidIBA 05/2005 - 10/2004
2	Fluconazole (Zonal)FDA LinkGeneric 05/2005 - 10/2004
1	Meropenem (Merrem)FDA LinkGeneric 10/2021
1	Vancomycin FDA LinkGeneric 10/2021
1	Anti-Infective Agents (Microbicides)IBA 10/2021
1	Cytarabine (Cytosar-U)FDA LinkGeneric 03/2020
1	ceftazidime drug combination avibactamIBA 01/2020
1	carbapenemaseIBA 01/2020
1	TriterpenesIBA 01/2020
1	tazobactam drug combination ceftolozaneIBA 01/2019
1	PorinsIBA 01/2019
1	eravacyclineIBA 01/2018
1	CarbohydratesIBA 05/2017
1	VaccinesIBA 01/2017
1	LipopeptidesIBA 12/2015
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 08/2015
1	Annexin A1IBA 06/2014
1	Glucose (Dextrose)FDA LinkGeneric 09/2013
1	AgarIBA 09/2013
1	trypticase-soy broth (trypticase soy)IBA 09/2013
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 01/2011
1	Serine Proteases (Serine Protease)IBA 01/2011
1	Oxidants (Oxidizing Agents)IBA 01/2011
1	Blood Proteins (Serum Proteins)IBA 12/2010
1	Prealbumin (Transthyretin)IBA 12/2010
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 12/2010
1	28S Ribosomal RNAIBA 11/2008
1	beta-GlucansIBA 11/2008
1	Polysaccharides (Glycans)IBA 05/2007
1	galactoxylomannanIBA 05/2007

Therapy/Procedure

24	Therapeutics 01/2021 - 01/2002
2	Drug Therapy (Chemotherapy) 01/2017 - 02/2007
1	Vascular Access Devices (Arterial Line) 10/2021
1	Intravenous Infusions 01/2020